Author

Jiawen Hu

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

#gene editing Open access Oct 2026

Hybridization-Mediated Reversible sgRNA Caging Enables Tumor-Selective Gene Editing for Potentiating Antitumor Immunity via cGAS Demethylation.

This study provides a versatile paradigm for conditionally controlled gene editing and highlights the therapeutic potential of cGAS demethylation in reactivating cGAS-STING pathway for antitumor immunotherapy.

Hao-Yu Zhang, Ya-Jie Li, Ye-Han Wang et al. · Angewandte Chemie · 0 citations

#gene editing Oct 2026

Hybridization‐Mediated Reversible sgRNA Caging Enables Tumor‐Selective Gene Editing for Potentiating Antitumor Immunity via cGAS Demethylation

ABSTRACT Spatiotemporal precision remains a critical challenge against the gene editing technology used for disease treatment. We herein developed a tumor cell‐selective CRISPR/Cas9 gene editing system by introducing a complementary single‐stranded DNA (ssDNA) containing apurinic/apyrimidinic (AP) sites (AP‐ssDNA) alon...

Haoyu Zhang, Yajie Li, Yehan Wang et al. · Angewandte Chemie · 0 citations