Role of semaphorin 4f in cardiac fibroblasts to regulate matrix production through actin remodeling and YAP/TAZ activation
This study provides the first evidence demonstrating the functional role of Sema4f in cardiac fibroblast activation and fibrosis progression, and identifies a fibroblast-specific mechanism mediated by the Sema4f-actin cytoskeleton-YAP/TAZ axis, offering novel mechanistic insights into fibrosis regulation and revealing...