Author

Jinbu Wang

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Open access Sep 2026

PGS-GS: a framework integrating polygenic scores and genomic selection in animal breeding

It is demonstrated that PGS and PGS–GS algorithms achieve predictive accuracy competitive with genomic best linear unbiased prediction (GBLUP) while offering markedly higher computational efficiency, and incorporating PGS-derived prior information into weighted linear and non-linear models outperformed conventional wei...

Jin-Bu Wang, Li-Li Du, Zhi-Da Zhao et al. · Briefings in Bioinformatics · 0 citations

#gene editing Open access Sep 2026

Multi-layer Cis-molQTLs Reveal Regulatory Architecture and Enhance Heritability Explanation for Complex Traits in Cattle.

Genome-wide association study (GWAS) analyses have identified numerous loci associated with economic traits in cattle. Many of these loci reside in noncoding regions, and the regulatory mechanisms through which they influence complex traits remain poorly understood. Here, we integrated 657 RNA-seq libraries from 275 Hu...

Shiyuan Qiu, Li-Li Du, Bo-Yu Zhang et al. · Genomics, Proteomics & Bioin... · 0 citations