Author

Jing Gao

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Sep 2026

Relationship of the co-occurrence of sarcopenia and metabolic syndrome with cognitive trajectory deterioration in middle-aged and older adults: A national cohort study with causal forest analysis.

BACKGROUND Cognitive impairment constitutes a major public health burden in the aging population. Sarcopenia and metabolic syndrome are both highly prevalent in middle-aged and older adults. However, the impact of their co-occurrence on long-term cognitive trajectories remains unclear. OBJECTIVE To investigate the as...

Yan Chen, Ke-Wen Ma, Zi-Jia Meng et al. · Maturitas · 0 citations

Sep 2026

Combined associations of triglyceride-glucose index and biochemical sarcopenia index with cardiometabolic multimorbidity in middle-aged and older Chinese adults.

The triglyceride-glucose index is a robust and independent predictor of incident cardiometabolic multimorbidity and shows a very small incremental improvement over the TyG index alone, though the clinical significance is uncertain and requires external validation.

Yan Chen, Jun Chen, Zi-Jia Meng et al. · Maturitas · 0 citations

Aug 2026

Integrated bulk and single-cell transcriptomic analyses identify senescence-related hub genes and microenvironmental remodeling in sarcopenia

PCK1, EGFR, and MAPKAPK3 are senescence-related candidate biomarkers in sarcopenia and may reflect distinct yet interconnected biological processes involving metabolic adaptation, stromal remodeling, immune microenvironment alteration, and myogenic dysregulation.

Yan Chen, Ke-Wen Ma, Tian Huang et al. · Functional & Integrative Gen... · 0 citations

Aug 2026

Association of the triglyceride glucose-Chinese visceral adiposity index with incident sarcopenia among middle-aged and older adults with diabetes: a prospective cohort study

Elevated baseline and cumulative TyG-CVAI are associated with new-onset sarcopenia in middle-aged and older Chinese adults with diabetes.

Yan Chen, Ting-Yu Gao, Jing Gao et al. · Endocrine · 0 citations

Review Open access Jul 2026

Endoplasmic reticulum autophagy in inflammatory diseases

This review summarizes the key receptors, regulatory mechanisms, and the latest research on ER-phagy in various inflammation-related diseases, aiming to draw academic attention to the important value of ER-phagy in inflammatory diseases.

Chunxia Wang, Jing Gao, Changsheng Guo et al. · Frontiers in Immunology · 0 citations