Author

Jin‐Song Gong

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#protein folding Sep 2026

Engineered Tumor-Homing Escherichia coli for Localized Hyaluronic Acid Degradation and Stromal Remodeling in Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) accumulates vast amounts of hyaluronic acid (HA), generating a rigid, high-pressure stroma that blocks drug delivery and infiltration. Although hyaluronidase (HAase) can dismantle this barrier, systemic administration of HAase depletes HA from healthy tissues and causes dose-limi...

Shuai Gao, Ting-Ting Liu, Chang-Hao Tian et al. · Macromolecular Bioscience · 0 citations

Jul 2026

Cooperative enzymatic depolymerization of poly(lactic acid) nonwoven fabrics using a newly identified cutinase Cr14CLE and proteinase K

The development of efficient enzymatic strategies for poly(lactic acid) (PLA) recycling remains limited by the insufficient catalytic performance of single enzymes and the lack of mechanistic understanding of multi-enzyme cooperation. In this study, a newly screened cutinase, Cr14CLE, was characterized and, for the fir...

Ying Sun, Jingwen Zhang, Guoqiang Zhang et al. · Textile research journal · 0 citations