Skip to content
Log in

Author

John P. Manis

View on Semantic Scholar

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Jul 2026

Non-genotoxic transplantation and in vivo selection through epitope editing

Epitope editing of KIT enables antibody-based, non-genotoxic conditioning that selectively enriches therapeutic BCL11A-edited haematopoietic stem/progenitor cells, supports durable engraftment, preserves clonal diversity and enhances induction of fetal haemoglobin, a therapeutic approach for conditions such as sickle cell disease and β-thalassemia.

G. Casirati, Andrea Cosentino, Marta Freschi et al. · 0 citations
#gene editing Open access Aug 2026

Analysing long-read CRISPR experiments with CRISPRLungo.

This work presents CRISPRLungo, a computational pipeline specifically designed for long-read amplicon sequencing of gene edited samples that incorporates unique molecular identifier-based error correction and statistical filtering to distinguish true editing events from background noise, enabling robust detection of small indels and structural variants.

Gue-Ho Hwang, Benjamin Vyshedskiy, Timothy M. Barry et al. · 0 citations