Author

Jordan Tanley

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Open access Sep 2026

The reduction in blood pressure required to reduce arterial stiffness components in SPRINT: A randomized controlled trial.

Background: We previously demonstrated that intensive blood pressure (BP) control reduces total pulse wave velocity (T-PWV), through a load-dependent (LD-PWV), but not structural mechanism (S-PWV). We examined the extent to which changes in supine systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP)...

Theodore M. Deconne, Jordan Tanley, Ryan J. Pewowaruk et al. · American Journal of Physiolo... · 0 citations

Open access Aug 2026

Dissecting Alzheimer's proteomic landscape through NULISA profiling of brain cell‐specific extracellular vesicles

Blood‐based biomarkers are essential for early detection, monitoring, and therapeutic development in Alzheimer's disease (AD) and related dementia (ADRD), but current assays lack brain cell specificity and sensitivity to low‐abundant proteins.

Ashish Kumar, Mitu Sharma, Yi-Xin Su et al. · Alzheimer's & Dementia · 0 citations