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Author

Jorge Rodrigues de Sousa

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#protein folding Review Open access Nov 2026

Astrocytic endoplasmic reticulum stress as an amplifier of neuroinflammation and neurodegeneration in Alzheimer’s disease: a narrative review

Alzheimer’s disease (AD) is increasingly recognized as a multicellular neuroimmune disorder in which proteostatic failure, metabolic dysfunction, and sustained glial activation interact to accelerate synaptic loss. This narrative review examines endoplasmic reticulum (ER) stress in astrocytes as a mechanistic link amon...

Baraci da Silva Lima, Yan Thiago Paes dos Santos, Gabriel Costa Farias et al. · 0 citations

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