It is demonstrated that PGS and PGS–GS algorithms achieve predictive accuracy competitive with genomic best linear unbiased prediction (GBLUP) while offering markedly higher computational efficiency, and incorporating PGS-derived prior information into weighted linear and non-linear models outperformed conventional wei...
Jin-Bu Wang, Li-Li Du, Zhi-Da Zhao et al.· Briefings in Bioinformatics· 0 citations
Genome-wide association study (GWAS) analyses have identified numerous loci associated with economic traits in cattle. Many of these loci reside in noncoding regions, and the regulatory mechanisms through which they influence complex traits remain poorly understood. Here, we integrated 657 RNA-seq libraries from 275 Hu...
Shiyuan Qiu, Li-Li Du, Bo-Yu Zhang et al.· Genomics, Proteomics & Bioin...· 0 citations
Cell-resolved maps provide mechanistic insight into how genetic variation shapes economically important traits, offering a valuable resource for functional studies, cell-informed precision breeding strategies, and the design of large-scale molecular phenotyping.
Bo-Yu Zhang, Shiyuan Qiu, Zhen-Wei Du et al.· Journal of Animal Science an...· 0 citations