Author

Justin B. Siegel

2 papers indexed here

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Open access Aug 2026

Flux Rewiring Enables Native D-Glucosamine Production in Escherichia coli.

Native amino sugar biosynthesis in E. coli provides a controllable framework for producing chemically distinct sugars through endogenous metabolism and establishes a generalizable strategy for engineering amino sugar and other nitrogen-containing metabolite biosynthesis.

Dileep Sai Kumar Palur, Amey Bait, Bryant Luu et al. · Metabolic Engineering · 0 citations

#protein folding Open access Sep 2026

De novo Rubisco design with protein language models

Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) fixes the majority of carbon dioxide globally but is challenged with low specificity for CO2 versus O2 and low catalytic efficiencies. Traditional engineering efforts have remained difficult because folding, assembly, specificity, and catalysis are tightly coupl...

Alexander J. Kehl, Simon K. S. Chu, J. H. Pereira et al. · bioRxiv · 0 citations