Open access
Sep 2026
DDX41 mutations establish a separate entity in acute myeloid leukemia with distinct survival outcomes
Recurrent germline variants in DDX41 represent the most common inherited predisposition to adult myeloid neoplasms, occurring in approximately 3% – 5% of patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). 1,2 Clinically, patients with DDX41 ‐ mutated AML are typically older at diagnosis, pred...
Carolin Seeling, Maral Saadati, D. Späth et al.
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