Author

K. Josephs

2 papers indexed here

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Open access Sep 2026

TMEM106B is a selective modulator of TDP‐43 pathology in Alzheimer's disease

Co‐pathologies – including Lewy body, vascular, and TDP‐43 lesions – are common in Alzheimer's disease (AD), contributing to its clinical and pathological heterogeneity. Genetic risk factors may drive mixed pathology presentation, but their influence on the development of specific co‐pathologies remains unclear.

Madison M. Reeves, Anna Calliari, Tiffany W. Todd et al. · Alzheimer's & Dementia · 0 citations

Open access Jul 2026

Diffusion MRI Is More Sensitive Than Tau PET and Regional Volume Loss in Corticobasal Syndrome

Background: Corticobasal syndrome (CBS) is a neurodegenerative syndrome that often results from a 4-repeat tauopathy. Abnormalities on tau PET, structural MRI, and diffusion MRI (dMRI) have been observed in CBS, although no prior work has systematically compared the relative sensitivity of these modalities. In addition...

Yuqi Tian, Ryota Satoh, Val J. Lowe et al. · medRxiv · 0 citations