OBJECTIVE
We aimed to evaluate the association between bariatric surgery (BS) and the incidence of dementia and Parkinson's disease. To assess consistency with established benefits of BS, we examined its association with cardiovascular disease, obesity-associated cancers, and all-cause mortality.
METHODS
We conducted...
S. Shiekh, D. Papamargaritis, J. Goldney et al.· International Journal of Obe...· 0 citations
Abstract Background Scaling innovations for people living with multiple long-term conditions (MLTCs or multimorbidity) remains challenging, particularly in primary care, where organisational capacity, infrastructure, and local contexts vary widely. There is limited empirical understanding of the implementation work nee...
Sarah Chew, Natalie Armstrong, G. Maniatopoulos et al.· International Journal for Qu...· 0 citations
Fibrotic interstitial lung disease (fILD) is often diagnosed late and can be difficult to recognise in people with common respiratory or cardiac long-term conditions. We examined whether baseline routine blood-test profiles and leucocyte telomere length (LTL) identified groups at higher risk of subsequent hospital-...
G. Lough, L. Wain, A. Meffen et al.· ERJ Open Research· 0 citations
The global prevalence of diabetes is rising rapidly, with the steepest increases and greatest unmet need occurring in low-income and middle-income countries. Despite strong evidence that early detection and continuous management reduce morbidity and mortality, many health systems face persistent gaps in diagnosis, trea...
Partha Kar, H. Sathanapally, P. Aschner et al.· The Lancet Diabetes and Endo...· 0 citations
Background Hypertension (HTN) is a leading risk factor for cardiovascular (CV) and renal morbidity and mortality, yet blood pressure (BP) control remains suboptimal worldwide. Understanding management patterns, especially among patients with coexisting Type 2 diabetes mellitus (T2DM), chronic kidney diseases (CKDs), or...
K. Khunti, M. Arıcı, Carol A. Pollock et al.· International Journal of Hyp...· 0 citations
Objective To examine and contrast the associations of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) with the risk of cardiometabolic multiple long-term conditions (cMLTC) and evaluate their incremental predictive utility. Patients and Methods The study analyzed 2233 adults (mean age 63; 1009 (45.2%) men)...
S. Seidu, S. Kunutsor, K. Khunti· Mayo Clinic Proceedings: Inn...· 0 citations
BACKGROUND
Individually, sodium-glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP-1RA and SGLT2i therapy in this p...
Hussain Salim, Shaheer Qureshi, G. Gulsin et al.· Diabetes, obesity and metabo...· 0 citations
MLTCs burden was a stronger determinant of mortality risk than CVD subtype alone, andFindings support moving beyond single-disease models towards integrated, MLTC-informed care, and pandemic preparedness.
Yogini V. Chudasama, S. Shabnam, K. Khunti et al.· Journal of public health· 0 citations
To identify low‐ and high‐risk intervals for major adverse cardiovascular events (MACE) and all‐cause mortality according to lipid ratios in adults with Type 2 diabetes mellitus (T2DM), stratified by sex.
E. Carretero-Anibarro, J. Quesada, Manuel A. Ruiz-Quintero et al.· Diabetes, obesity and metabo...· 0 citations
Moderate to high certainty evidence supports discontinuation of drugs for adults with overweight or obesity because of adverse events to be highest with orforglipron, naltrexone-bupropion, liraglutide, phentermine-topiramate, CagriSema, and oral semaglutide.
Kai-Lei Nong, Qingyang Shi, Xinran Xie et al.· British medical journal· 5 citations
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