Solute Carrier Family 1 Member 5 (SLC1A5)-dependent glutamine transport regulates macrophage senescence and efferocytosis during liver regeneration
The findings reveal a novel ‘Slc1a5-glutamine-senescence-efferocytosis’ axis that dictates macrophage driven tissue repair and highlights glutamine supplementation and senolytics therapy as promising clinically strategies to accelerate liver regeneration.