Open access
Sep 2026
Brain‐derived plasma p‐tau217 shows enhanced dynamic range for Alzheimer's disease neuropathological change
Plasma phosphorylated tau (p‐tau), particularly p‐tau217, is a highly specific biomarker of Alzheimer's disease (AD) pathology. However, plasma p‐tau217 can be elevated in rare non‐AD conditions. Brain‐derived (BD) p‐tau217 may reduce these off‐target effects, but its performance against neuropathology has not been eva...
Marisa N. Denkinger, W. Brum, A. Leuzy et al.
· Alzheimer's & Dementia · 0 citations