Deciphering Novel Transcriptional Wiring in Colorectal Cancer: An Integrative Bioinformatic and Experimental Study
Experimental results showed melatonin reduces SW480 viability with an IC₅₀ of 2.63 mM and lowers BUB1 and CCNA2 expression in different manners of concentration-dependency, while NCAPG remains unchanged, and selective repression of two NF-Y targets with sparing of a non-target is consistent with reduced NF-Y-dependent...