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Author

Kohsuke Yoshida

2 papers indexed here

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Open access Sep 2026

Baseline CSF tau and short‐term clinical change during lecanemab therapy: A prospective real‐world cohort study in Japan

Abstract INTRODUCTION Real‐world prognostic evidence for cerebrospinal fluid (CSF) biomarkers during lecanemab therapy remains limited. We examined whether baseline CSF phosphorylated tau 181 (pTau181), total tau, and amyloid beta (Aβ) 42/Aβ40 were associated with 6‐month clinical change. METHODS This prospective singl...

R. Takahashi, Tetsuo Kashibayashi, Jun Fujita et al. · 0 citations
Sep 2026

Lower baseline cerebrospinal fluid amyloid-β 42 is associated with amyloid-related imaging abnormalities during real-world lecanemab treatment.

Lower Aβ42 was associated with subsequent ARIA, but the internally derived cutoff requires external validation, and the internally derived cutoff requires external validation.

R. Takahashi, Tetsuo Kashibayashi, Jun Fujita et al. · 1 citation

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