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Koichiro Watanabe

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Open access Sep 2026

Comparison of depressive symptoms and anxious distress between major depressive disorder and bipolar disorder using the CUDOS‐A

Abstract Aim Anxious distress is a clinically important specifier associated with adverse outcomes in mood disorders. This study aimed to compare the prevalence of anxious distress and overall depressive symptoms between patients with major depressive disorder (MDD) and bipolar disorder (BD) using validated self‐report...

Kazufumi Oishi, Yasuyuki Matsumoto, Yumi Aoki et al. · 0 citations
Open access Sep 2026

Prevalence of Treatment‐Resistant Schizophrenia: A Nationwide Multicenter Study

The prevalence of treatment‐resistant schizophrenia (TRS) among patients with schizophrenia remains insufficiently characterized using nationwide data and standardized diagnostic criteria.

Yusuke Arai, Toru Horinouchi, Hiroyuki Muraoka et al. · 0 citations
Case report Open access Sep 2026

Three Adult Cases of ADHD With Comorbid Tic Symptoms Successfully Treated With Guanfacine Monotherapy

Three adult male patients with childhood‐onset ADHD and chronic tic symptoms who showed a rapid and significant improvement in tics with low‐dose extended‐release guanfacine (GXR) monotherapy suggest that GXR can effectively treat both ADHD and tic symptoms in adults.

K. Tada, T. Tada, T. Tsuboi et al. · 0 citations
Open access Jul 2026

Royal jelly ameliorates age-associated stem cell dysfunction with Chi3l1-mediated increase in CD206-positive macrophages

It is shown that dietary RJ enhances stem/progenitor cell activity with age- and tissue-dependent Chi3l1 -mediated increases in CD206-positive macrophages, suggesting that Chi3l1 is a physiologically regulated immune mediator, rather than a pathogenic factor in disease contexts, highlighting the importance of mechanis...

Y. Kande, Y. Ikuno, Ayano Narumoto et al. · 0 citations

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