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Author

L. Călinoiu

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Review Open access Oct 2026

From Gut Microbiome to Aging Brain: Butyrate as a Neurogeroscience Effector.

Aging-related cognitive decline is increasingly linked to disruption of the microbiome-gut-brain axis, in which age-associated dysbiosis progressively reduces butyrate production, a short-chain fatty acid and central neuroactive metabolite generated by bacterial fermentation of dietary fiber. Experimental studies indic...

L. Mitrea, L. Călinoiu, G. Martău et al. · 0 citations
Review 2026

Microbiota, fermentation, and metabolite biotransformation: Pathways to functional foods and personalised nutrition.

The mechanistic links between microbial metabolism and host health are explored, emerging fermentation technologies for targeted metabolite production are reviewed, and industrial case studies demonstrating the transition of precision fermentation from research to commercial applications are highlighted.

L. Mitrea, G. Martău, L. Călinoiu et al. · 0 citations

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