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Author

L. Chong

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2 papers indexed here

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Open access Aug 2026

Spatial organisation of tumor-infiltrating B-cells informs immune checkpoint inhibitor response in Claudin 18.2-expressing gastric cancer.

PURPOSE Claudin 18.2 (CLDN18.2), a tight junction protein normally expressed in gastric epithelium and rendered accessible during malignant transformation, has emerged as a key therapeutic target. Here, we seek to characterize the immune microenvironment of CLDN18.2-expressing gastric cancer and identify immune feature...

Joseph J. Zhao, Choong-kun Lee, Allison S. Y. Chan et al. · 0 citations
Jul 2026

Spatiotemporal transcriptomics of human cardiovascular progenitors in pig hearts identifies Midkine as a positive regulator of neovascularization

It is shown that the engrafted cardiovascular progenitors progressively upregulated genes associated with cardiac maturation, oxidative metabolism, calcium handling and fibrosis resolution, and MDK is identified as a tractable target for therapeutic angiogenesis in ischemic heart disease.

Swarnaseetha Adusumalli, Kye Siong Leong, Samantha Lim et al. · 0 citations

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