Author

L. Davis

2 papers indexed here

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Aug 2026

A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway.

These datasets are a resource for identifying genes associated with type I IFN-related inborn errors of immunity and cancer and for developing therapies to modulate STING signaling in interferonopathies and other conditions of dysregulated type I IFN.

E. A. Thomsen, Jian Zhao, Ryo Narita et al. · Science Signaling · 0 citations

#protein folding Open access Aug 2026

β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments

How PilC/PilY1 can be retained on the fiber tip under enormous tensile loads generated during mechanical shear and T4P retraction is explained and how diverse T4P systems employ β-strand addition to license fiber assembly is demonstrated.

Taylor J. Ellison, Zoey R. Litt, Justin N. Applegate et al. · Proceedings of the National... · 0 citations