Open access
Aug 2026
Study objective Polygenic risk scores (PRS) are increasingly recognized for their potential to improve coronary artery disease (CAD) prediction beyond traditional clinical models. This study evaluated the utility of genome-wide association study (GWAS) - derived PRS and pathway-specific PRS (PS-PRS) in the Latvian popu...
E. Kanašniece, Elita Ozola, L. Bardina et al.
· American Heart Journal Plus:... · 0 citations
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Open access
Jul 2026
Background/Objectives: Perivascular spaces (PVS) are MRI-visible compartments surrounding cerebral vessels and are increasingly interpreted as markers of cerebral small-vessel disease and glymphatic-system dysfunction. PVS burden is multifactorial, with possible contributions from vascular risk, atrophy, white matter d...
Gvido Kārlis Skuburs, Kristīne Šneidere-Pītersa, A. Platkājis et al.
· Diagnostics · 0 citations
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Open access
Jul 2026
Background Chronic spontaneous urticaria (CSU) is a heterogeneous immune-mediated disorder characterized by recurrent wheals and/or angioedema. Despite advances in understanding its pathogenesis, robust biomarkers for disease stratification remain lacking. MicroRNAs (miRNAs) are key post-transcriptional regulators impl...
Lāsma Lapiņa, Katrīna Daila Neiburga-Vīgante, L. Gailīte et al.
· Frontiers in Immunology · 0 citations
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