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Author

L. Gailīte

3 papers indexed here

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Open access Aug 2026

Polygenic risk score for early identification of coronary artery disease in a real-world clinical setting within the Latvian patient population

Study objective Polygenic risk scores (PRS) are increasingly recognized for their potential to improve coronary artery disease (CAD) prediction beyond traditional clinical models. This study evaluated the utility of genome-wide association study (GWAS) - derived PRS and pathway-specific PRS (PS-PRS) in the Latvian popu...

E. Kanašniece, Elita Ozola, L. Bardina et al. · 0 citations
Open access Jul 2026

A Quantitative Assessment of MRI-Visible Perivascular-Space Burden Across the Cognitive Spectrum: Associations with APOE ε4 Status and Venous Sinus Volume

Background/Objectives: Perivascular spaces (PVS) are MRI-visible compartments surrounding cerebral vessels and are increasingly interpreted as markers of cerebral small-vessel disease and glymphatic-system dysfunction. PVS burden is multifactorial, with possible contributions from vascular risk, atrophy, white matter d...

Gvido Kārlis Skuburs, Kristīne Šneidere-Pītersa, A. Platkājis et al. · 0 citations
Open access Jul 2026

Detection of miRNA in chronic spontaneous urticaria patients - pilot study

Background Chronic spontaneous urticaria (CSU) is a heterogeneous immune-mediated disorder characterized by recurrent wheals and/or angioedema. Despite advances in understanding its pathogenesis, robust biomarkers for disease stratification remain lacking. MicroRNAs (miRNAs) are key post-transcriptional regulators impl...

Lāsma Lapiņa, Katrīna Daila Neiburga-Vīgante, L. Gailīte et al. · 0 citations

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