Abstract PR004: Characterization of patient-specific CHEK2 genetic variants in high-risk neuroblastoma
Neuroblastoma (NB) is the most common extra-cranial solid tumor in children and accounts for approximately 10% of pediatric cancer deaths. Next-generation sequencing studies of patients with high-risk NB identified multiple pathogenic/likely pathogenic (P/LP) germline and oncogenic somatic variants in the Checkpo...