Probing the pH- and Voltage-Driven Intramolecular Folding Dynamics of the c‑MycC52 Promoter i‑Motif at the Single-Molecule Level
Findings establish α-HL electrophysiology as a sensitive platform for distinguishing subtle differences in i-motif conformational stability, with potential applications in DNA secondary structure dynamics and disease-targeted diagnostic strategies.
Adina Cimpanu, Jonggwan Park, Yoonkyung Park et al.
· Analytical Chemistry · 0 citations