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Author

L. Tashireva

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Open access Oct 2026

Current Understanding of the Molecular Mechanisms of Resistance to Targeted Anti-HER2 Breast Cancer Therapy

This lecture summarizes current evidence on the molecular and genetic mechanisms of resistance to HER2targeted breast cancer (BC) therapies. Despite marked improvements in HER2-positive BC treatment, the efficacy of targeted therapy remains suboptimal. Within the first two years after completing combined therapy, 10-15...

O. Bragina, E. Y. Sitnikova, A. A. Nesynov et al. · 0 citations
Review Aug 2026

Predictors of immunotherapy response in gastric cancer: the role of the tumor microenvironment and integrative predictive models.

This review synthesizes current data on cellular, molecular, and systemic predictors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors.

E. Tsarenkova, A. Kalinchuk, E. Shmakova et al. · 0 citations

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