Review
Models: An Emerging Platform for Translational Cancer Research
M. Hidalgo, F. Amant, A. Biankin et al.
· 1 citation
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Efficacy Is Impacted by
Dual MEK and mTORC1/2 blockade resulted in synergistic antiproliferative effects in cell lines bearing alterations in KRAS/BRAF and PIK3CA/PTEN and a marked proapoptotic response to therapy was observed exclusively in wild-type TP53 colorectal cancer models.
Celina García-García, M. Rivas, Y. Ibrahim et al.
· 0 citations
Review
the MET gene for the treatment of non-small-cell
This review will focus on the MET pathway and its role in resistance to EGFR TK (tyrosine kinase) inhibitors, the different strategies of its inhibition, and the potential approaches to overcoming acquired resistance.
F. Gelsomino, F. Facchinetti, E. Haspinger et al.
· 0 citations