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Author

L. Mittelman

3 papers indexed here

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Open access Oct 2026

Preoperative risk stratification of discharge disposition using the RAPT score in brain tumor surgery.

PURPOSE Discharge planning following brain tumor resection is often variable, contributing to delays in care coordination after discharge. While structured discharge prediction tools are widely used in orthopedic and spine surgery, no standardized preoperative framework exists in neurosurgical oncology. We conducted an...

Samuel Latzman, Shoaib A. Syed, Griffin Thomas et al. · 0 citations
Open access Sep 2026

Quantitative stability of MGMT promoter methylation in recurrent glioma and implications for temozolomide rechallenge

O^6^-methylguanine–DNA methyltransferase (MGMT) promoter methylation is a key predictive biomarker for temozolomide (TMZ) response in glioma. MGMT status is routinely assessed at diagnosis; however, its utility at recurrence remains incompletely characterized. We aimed to quantify MGMT methylation stability and assess...

H. Noren, Gabriella Pelofsky, Brianna Suffren et al. · 0 citations
Review Jul 2026

Postoperative Seizure Prophylaxis in Intracranial Tumors: Evaluating the Role of Anti-Seizure Medication in Seizure-Naïve Patients

Routine ASM prophylaxis in seizure-naïve patients undergoing intracranial tumor resection is not supported by current evidence or clinical guidelines, and a selective, risk-based approach with short-term prophylaxis may be considered in patients with high-risk features.

N. Seenarine, Samuel Latzman, Laura Mittelman et al. · 0 citations

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