Postoperative Seizure Prophylaxis in Intracranial Tumors: Evaluating the Role of Anti-Seizure Medication in Seizure-Naïve Patients

Prognosis of acute symptomatic seizures and impact of prolonged treatment with anti-seizure medication.

OBJECTIVES Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti-seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond ho...

Prophylactic use of antiepileptics in spontaneous intracerebral hemorrhage: a systematic review and meta-analysis focusing on early seizures and clinical determinants

Management of Epilepsy in the Brain Tumour Patient: Current Concepts and Practical Approaches.

Brain Tumour-Related Epilepsy (BTRE) is among the most common, disabling and feared complications of primary and metastatic brain tumours. Seizures cause significant suffering, psychosocial burden, reduced quality of life and lead inevitably to the loss of a driving license. The mechanisms underlying BTRE are multifact...

Time-dependent predictors of seizure outcome in grade 1-2 glioma-related epilepsy.

This time-resolved analysis suggests that early seizure control is primarily influenced by surgical and tumor burden-related factors, whereas long-term seizure outcomes and recurrence appear to be predominantly determined by the clinical presentation at diagnosis rather than treatment-related variables.

Surgical Selection in Drug-Resistant Epilepsy: A Contemporary Evidence-Based Review of Patient Stratification, Presurgical Evaluation, and Surgical Outcomes

Continued advances in imaging, electrophysiology, minimally invasive techniques, and neuromodulation are transforming the management of DRE and facilitating increasingly individualized treatment strategies.

Drug-Resistant Epilepsy: Definitional criteria and indications for surgical treatment

The evidence supports the International League Against Epilepsy definition based on failure of two tolerated, appropriately chosen and adequately used antiseizure medication schedules to achieve sustained seizure freedom, provided that pseudoresistance has been excluded.