Author

L. S. Qi

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#gene editing Open access Oct 2026

Programmable Surface Receptor-Mediated Cell Targeting with Designer Antibody-Routed Nanoparticles (DARTs)

The DART platform provides a universal tool for rapidly profiling unique, targetable antigens and leveraging them for precision editing applications, and function in the fetal murine nervous system, empirically identifying CD56 as a previously uncharacterized surface antigen enabling editing in hard-to-transduce neural...

Goldie V. Roth, Isabella R. Gengaro, N. Ahmadian et al. · bioRxiv · 0 citations

Open access Sep 2026

Charge-switching ionizable lipids lower the toxicity of lipid nanoparticles.

Lipid nanoparticles (LNPs) have great potential as nucleic acid delivery vehicles; however, they trigger the production of inflammatory cytokines, which limits their medical applications. Developing non-inflammatory LNPs is challenging because the LNP's ionizable lipid and the process of endosomal disruption are the ma...

Deng-Pan Liang, Ya-Lin Qi, He-Song Han et al. · Nature Nanotechnology · 0 citations