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Li-Guo Zhu

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Open access Oct 2026

Recurrent intrahost G-gene haplotype structures suggest potential co-transmission in RSV-A.

Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization worldwide. Its molecular epidemiology rests on consensus G-gene sequences, which capture only the dominant virus in each infection. Deep sequencing reveals far more variation inside each host. Linking those variants to one another gives a fi...

Jing-Qi Yang, Yu-Hua Liao, Lu-Yao Qin et al. · 0 citations
#protein folding Open access Oct 2026

Global resurgence of norovirus GII.17[P17] accompanies shifting phylogeographic connectivity patterns: surveillance in Jiangsu, 2023–2025

Inferred phylogeographic connectivity patterns indicate that the primary centers of GII.17[P17] lineage dispersal have shifted from East Asia to Northwest Europe and carries lineage-specific amino acid substitutions in antigenic epitopes temporally associated with its global expansion.

Chu-Chu Li, Jin-Bo Xiao, J. Ai et al. · 0 citations
Clinical trial Open access Sep 2026

Dissociation between humoral and multi-omic immune responses to inactivated COVID-19 vaccination in patients with pulmonary tuberculosis

Despite comparable short-term neutralizing antibody responses, PTB patients receiving anti-tuberculosis treatment exhibited attenuated and distinct systems-level proteomic and transcriptomic remodeling after inactivated COVID-19 vaccination compared with healthy controls, suggesting a predominance of nominal negative a...

Zhi-Jie Jiang, Peng-Fei Jin, Xiao-Rui Nie et al. · 0 citations
Open access Aug 2026

Serum Escape Landscape of SARS-CoV-2 Omicron JN.1 and XEC RBD Under COVID-19 Vaccine Breakthrough Immunity in China

The findings suggest that SARS-CoV-2 antigenic evolution follows the pattern of multiple pathways within a constrained space, providing new insights into the adaptive mechanisms of Omicron-derived variants under hybrid immune pressure.

Cheng-Wei Shao, Jian-Guang Fu, Fei Deng et al. · 0 citations

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