Liyuan Jing

Ternary In2O3/ZnIn2S4/CdS heterojunction-based APE1-assisted "AND" logic gate photoelectrochemical biosensor for dual-miRNA detection.

Photoelectrochemical biosensing has become a powerful technique for disease monitoring and therapeutic tracking. Most existing photoelectrochemical platforms are only capable of detecting a single biomarker, which limits their effectiveness in comprehensive disease management. To address this challenge, we developed a...

DNAzyme assisted self-feedback electrochemiluminescence signal amplification for the detection of miRNA-622

PTX3 induces the expression of PD-L1 and promotes breast cancer immune escape.

It is demonstrated that PTX3 promotes immune evasion in breast cancer by upregulating PD-L1 by increasing the expression of the E3 ligase RNF216 and caused Beclin-1 degradation, which suppressed autophagy, thereby preventing autophagy-mediated PD-L1 degradation.