ABSTRACT Steroids from myxobacteria remain largely underexplored compared to other natural product classes, leaving a significant gap in our understanding of their biosynthetic diversity, evolutionary trajectories, and pharmacological potential. To address this, we conducted a systematic genomic survey of myxobacterial...
Bing-Jie Fan, Luo Niu, Teng Liu et al.· Applied and Environmental Mi...· 0 citations
Redox-based chemical warfare is a primary driver of microbial community assembly. Here, we show that the predatory bacterium Myxococcus xanthus employs a spatial division of labor between two inducible monofunctional catalases, mxKatB and mxKatE, to overcome prey-derived hydrogen peroxide (H₂O₂). Quantitative transcrip...
D. Sheng, Xuan-qi Zhang, Xin-yao Yan et al.· bioRxiv· 0 citations
ABSTRACT Peptidylprolyl isomerase (PPIase) catalyzes the rate-limiting step of proline cis-trans isomerization during protein folding. In bacteria, multiple PPIases are commonly present and participate in diverse physiological processes. Myxococcus xanthus DK1622 possesses as many as 17 PPIase genes. We previously repo...
Tian-yu Wan, Rui-You Chen, Zi-Ye Zhou et al.· Applied and Environmental Mi...· 0 citations
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