Jul 2026
HNRNPF-driven retention of exon 14 in HIF1A pre-mRNA promotes breast cancer metastasis.
The HNRNPF/HIF1A-L/CXCR4/AKT axis as a central regulatory circuit controlling breast cancer metastasis is elucidated and it is suggested that correcting the aberrant splicing of HIF1A may represent a novel therapeutic strategy for cancer.
Mengzhen Huang, Jiang Lei, Wei Wu et al.
· Biochimica et Biophysica Act... · 0 citations