Author

Lucas M. Waldburger

2 papers indexed here

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Oct 2026

Orchestrating polyketide synthase-derived aldehyde metabolism for Streptomyces biomanufacturing.

Advances in metabolic engineering have enabled the integration of diverse non-native reactions into microbial hosts, providing sustainable alternatives to petrochemical manufacturing. We previously developed a modular polyketide synthase (PKS)-based platform in Streptomyces albus for producing 17 diols, amino alcohols,...

Q. Dan, Xi-Na Wang, Yan Chiu et al. · Metabolic Engineering · 0 citations

#protein folding Open access Sep 2026

Active learning enables evolutionary discovery and characterization of fungal transcriptional activators

Biological discovery and design are increasingly guided by predictive models trained on data from high-throughput technologies rather than costly experiments. However, existing datasets are often biased by overrepresentation of model organisms, causing models to fail in evolutionary studies of non-model species....

Lucas M. Waldburger, Hunter M. Nisonoff, Marissa A. Zintel et al. · Genome Biology · 0 citations