Summary The adult central nervous system has limited regenerative capacity, with retinal ganglion cells (RGCs) particularly refractory to repair. The extracellular glial environment can critically influence neuronal survival and regenerative responses. Here, using cross-species co-culture, conditioned-medium approaches...
Xandra Pereiro, N. Ruzafa, Laura Prieto-López et al.· iScience· 0 citations
Post-translational modifications critically regulate extracellular molecular recognition, yet their roles in intrinsically disordered proteins remain poorly defined. Here, we integrate glycoproteomics, NMR, and cellular assays to reveal how glycosylation shapes the interaction network of osteopontin (OPN), a highly g...
I. A. Bermejo, D. del Balzo, M. Azkargorta et al.· JACS Au· 0 citations
It is described that downregulation of WNK1 through RNA interference in HEK293 cells led to a two-fold decrease in cell-surface GLUT1 abundance, concomitant with a 40% decrease in glucose uptake.
A. Henriques, Paulo Matos, A. S. Carvalho et al.· Cells· 0 citations
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