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M. Boerma

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Open access Sep 2026

Plasma-Derived Extracellular Vesicles as Systemic Mediators of Radiation Response and Radiation Mitigation by Activated Protein C in a Rat Model

Radiological emergencies necessitate biomarkers that not only estimate absorbed ionizing radiation (IR) dose but also guide timely interventions to prevent or delay multi-organ injury. Conventional LC–MS-based metabolomics of bulk plasma is constrained by matrix effects that mask low-abundance species. Extracellular ve...

Shivani Bansal, Sunain Deol, Meth M. Jayatilake et al. · 0 citations
Open access Jul 2026

A Comprehensive DNA Methylome BodyMap across 12 Organs/Tissues from Spaceflight Mice

A comprehensive DNA methylome BodyMap is constructed across 12 organs or tissues from mice exposed to long-duration spaceflight across three time points, elucidating the tissue specificity of epigenetic changes and essential for developing biomarkers and countermeasures to safeguard astronaut health during extended mis...

Zhong Chen, Chirag Nepal, Xiao W. Mao et al. · 0 citations

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