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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

M. Coelho

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2 papers indexed here

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Open access Sep 2026

Structure-function analysis of PI3K signalling cascade base editing screens in cancer cells

Knowledge of protein structure and function underpins rational drug discovery, yet many targets lack known selectively druggable sites. Furthermore, the identification of secondary druggable sites offers a strategy to overcome drug resistance. Fragment-based drug discovery (FBDD) can identify new ligandable binding poc...

Katrina McCarten, Bárbara Abreu, Benoit Baillif et al. · 0 citations
#gene editing Open access Sep 2026

CRISPR-enhanced assessment of variants of unknown significance nominates oncology therapeutic targets and drug repositioning opportunities

CRISPR-VUS combines dependency-based rare-variant discovery with evidence-guided prioritisation to nominate candidate drivers, therapeutic targets and drug-repositioning hypotheses to nominate candidate drivers, therapeutic targets and drug-repositioning hypotheses.

A. Savino, Athanasios Oikonomou, Francesca Perrone et al. · 0 citations

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