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M. Haydell

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Open access Sep 2026

Single-Stranded Interruptions in the T7 Promoter Non-Template Strand Exhibit Unexpected Transcription Behavior.

Structurally, small gaps may disrupt essential hydrogen bonding while larger gaps may increase promoter interaction with T7RNAP, thereby improving binding and initiation while hindering promoter release, and suggest novel strategies for DNA-based transcriptional control in bio-hybrid systems.

M. Haydell, Viktoria Steuper, Michael Famulok · 0 citations

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