Discovery and Design of YTHDF2-Selective and Pan-YTHDF Inhibitors for m6A Binding by the YTH Aromatic Cage
The results further define pharmacological molecular comprehensions for paralog-dependent engagement of m6A in RNA by the aromatic cage for the selective modulation of YTHDF functions.
Vilbert Sikorski, Joni Salo, Simona Selberg et al.
· ACS Omega · 0 citations