OBJECTIVE
Abnormalities in posteriorly dominant resting-state eyes-closed electroencephalographic (rsEEG) alpha rhythms are associated with cerebrospinal fluid (CSF) tau neuropathology and Mini-Mental Status Examination (MMSE) score, reflecting global cognition, in patients with mild cognitive impairment due to Alzheim...
C. Del Percio, R. Lizio, G. Noce et al.· Clinical Neurophysiology· 0 citations
Interindividual variability in psychotropic drug response contributes to treatment failure, adverse drug reactions, and repeated medication adjustments. Pharmacogenetics supports precision prescribing by identifying genetic variants associated with drug metabolism, efficacy, and tolerability, and evidence-based recomme...
T. Prodi, Maria Gabriela Nielsen, Floriana De Cillis et al.· Pharmaceuticals· 0 citations
These network-specific, hemisphere-sensitive measures may serve as biomarkers for diagnosis, tracking, and prognosis of cognitive decline, and could inform personalized network-targeted neuromodulation in AD.
G. Bertazzoli, E. Canu, C. Bagattini et al.· Alzheimer's Research & T...· 0 citations
Ratios combining biomarkers of both amyloid and tau, such as Aβ42/pTau, consistently outperformed individual biomarkers in detecting amyloid and tau PET positivity and enhanced clinical utility by highlighting ambiguous cases requiring further assessment.
Sophie Mutel, F. Ribaldi, Augusto J. Mendes et al.· Alzheimer's Research & T...· 0 citations
This study provided a valuable insight into the heterogeneity of EOAD and LOAD, extending current understanding of the differential involvement of brain regions and highlighting the importance of hypothalamic involvement as a potential target for further investigation in conjunction with clinical assessment.
Giulia Quattrini, Martina Bocchetta, C. Bagattini et al.· GeroScience· 0 citations
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