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M. Ramste

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Open access Sep 2026

An in vitro System for Studying Osteochondrogenic Differentiation of Smooth Muscle Cells and Modeling Intimal Vascular Calcification

The osteochondrogenic differentiation assay results in a strong calcification phenotype together with a disease-associated CMC-like transcriptional state, providing a reliable in vitro model for mechanistic investigation of SMC phenotypic transition and prioritization of candidate regulators.

J. Monteiro, Matthew D. Worssam, Wen-Duo Gu et al. · 0 citations

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