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M. Safari

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Open access Oct 2026

Domain-aligned self-supervision: CT-specialized DINOv3 enhances PET/CT tumor segmentation.

OBJECTIVE This study investigates how domain-aligned self-supervised pretraining influences downstream PET/CT tumor segmentation, with a focus on disentangling the roles of domain proximity and pretraining dataset scale. Approach: We compared nnU-Net segmentation models initialized from random weights or from DINOv3 en...

Yu-Nong Lin, Shan-Song Wang, Yu-Heng Li et al. · 0 citations
Open access Sep 2026

Cardiac Substructure Dose Quantification and Optimization in Left-Sided Lung Cancer Radiotherapy.

BACKGROUND As curative-intent radiation therapy provides excellent local control for lung tumors, patients are surviving longer to experience treatment-associated adverse cardiac events. Patients treated for left-lung tumors are particularly vulnerable due to the heart's anatomical proximity. While the whole heart is c...

Vanessa L. Wildman, Richard L. J. Qiu, K. Luca et al. · 0 citations
Preprint Aug 2026

MRI super-resolution in ten sampling steps using a diffusion bridge model

Objective. MRI provides excellent soft-tissue contrast, but long acquisition times can cause patient discomfort and lead to motion artifacts, forcing a trade-off between spatial resolution and scan time. Diffusion-based super-resolution (SR) reconstructs high-resolution (HR) images from low-resolution (LR) inputs, but...

M. Safari, Han Yu, Zach Eidex et al. · 0 citations
Review Aug 2026

Foundation models in medical image analysis: A systematic review and quantitative analysis.

This review provides a comprehensive and structured synthesis of FMs in medical image analysis by systematically organizing studies into two primary categories: vision-only foundation models (VFMs) and vision-language foundation models (VLFMs), based on their architectural foundations, training strategies, and downstre...

P. Rajendran, M. Safari, Wen-Feng He et al. · 0 citations
Open access Aug 2026

Low‐dose CT imaging using a regularization‐enhanced efficient diffusion probabilistic model

Low‐dose CT (LDCT) imaging reduces patient radiation exposure but introduces elevated noise levels that degrade image quality and undermine downstream clinical tasks such as diagnosis and quantitative analysis. Existing denoising approaches often require extensive diffusion steps that impede real‑time clinical applicab...

Qiang Li, M. Safari, Shansong Wang et al. · 0 citations
Open access Aug 2026

Motion Artifact-Aware Self-Supervised Representation Learning for 3D Brain MRI Motion Artifact Reduction.

Results indicate that SSRL-MAR provides a robust and scalable image-domain solution for 3D brain MRI motion correction, enabling reliable structural quantification in large-scale neuroimaging studies without requiring prospectively acquired pairs or acquisition-specific calibration.

M. Safari, Shan-Song Wang, Zach Eidex et al. · 0 citations
Preprint Aug 2026

Text-Guided Refinement of Multi-sequence Glioma Subregion Segmentation with a Vision-Language Foundation Model

Adapting a 3D vision-language foundation model for text-guided brain tumor segmentation refinement of glioma subregion segmentations suggests text-dependent contour editing rather than nonspecific post-processing, supporting further evaluation as a clinician-in-the-loop tool.

Zach Eidex, Yunyan Lin, M. Safari et al. · 0 citations

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