Author

M. Steinmetz

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Open access Oct 2026

Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction.

Accurate prediction of T cell receptor (TCR) reactivity is a long-standing goal in immunology. Here, we asked whether functional validation of TCR-peptide-major histocompatibility complex (MHC) (TCR-pMHC) pairs at scale alters performance estimates of TCR-pMHC reactivity prediction models. We developed a TCR rapid asse...

Marius Messemaker, Bjørn P. Y. Kwee, Živa Moravec et al. · Immunity · 0 citations

Open access Sep 2026

Proximity labeling puts ZFP36L1 as central hub for posttranscriptional regulation networks in T cells

Using proximity labeling, a comprehensive interactome map of the RBP ZFP36L1 is presented, demonstrating the versatility of interactions and their possible functioning during T-cell activation.

Anouk P. Jurgens, Branka Popović, Floris P. J. van Alphen et al. · Life Science Alliance · 0 citations