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M. V. van Osch

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Open access Jul 2026

Arterial spin-labeling-based exchange time mapping for differentiation of high-grade glioma and brain metastases

In this exploratory study, ASL-derived Tex suggests stronger BBB alterations in peritumoral tissue of high-grade gliomas compared with brain metastases and supports ASL-based BBB mapping as a complement to DSC leakage imaging.

Philipp Raffler, Gabriel Hoffmann, M. Günther et al. · 0 citations
Preprint Sep 2026

Data-Efficient Networks for Multi-Contrast MRI Reconstruction based on a Generalized Content/Style Prior

A modular framework, namely CoSMo-RecNet, for learning guided reconstruction models in the low-data regime, which is a reusable multi-contrast representation based on a content/style model that can be learned from large-scale, publicly accessible, unpaired multi-contrast image datasets, without available k-space data.

Chin-May Rao, E. Ilıcak, M. V. van Osch et al. · 0 citations
Open access Sep 2026

Feasibility of Spin‐ and Gradient‐Echo Dynamic Susceptibility Contrast MRI for Microvascular Characterization at 7 Tesla

Perfusion MRI, especially dynamic susceptibility contrast (DSC), is vital for glioma diagnosis and monitoring. While gradient‐echo DSC is the current recommended implementation, combined spin‐ and gradient‐echo (SAGE) DSC additionally allows for vessel size imaging (VSI) and has shown feasibility for microvascular char...

Karen N. van der Werff, D. van Dorth, Krishnapriya Venugopal et al. · 0 citations
Review Open access Aug 2026

Recent advances in arterial spin labeling MRI for imaging brain tumors.

The future potential of ASL MRI is seen not only in replacing contrast agents for perfusion assessment but also in providing additional information to the MRI exam, such as BBB integrity or the architecture of the vascular feeders.

Gabriel Hoffmann, M. V. van Osch · 0 citations

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