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Author

Manjunath B. Malshetty

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Jul 2026

Application of Proteogenomic Approaches for Refinement of the Entamoeba histolytica Reference Genome Using High Resolution Mass-Spectrometry Data

This is the first study to demonstrate proteogenomic integration of peptide-level evidence with genomic data substantially improves genome annotation in E. histolytica, expanding its known coding repertoire and providing functional insights into previously uncharacterized regions with implications for understanding par...

Manjunath B. Malshetty, Soumi Chowdhury, Shubhankar Pawar et al. · 0 citations
#protein folding Open access Aug 2026

In silico evaluation of deleterious nsSNPs in SOD1 and TARDBP genes associated with amyotrophic lateral sclerosis

Network and pathway analyses highlighted SOD1 and TARDBP as key nodes in ALS-related mechanisms, such as oxidative stress, RNA metabolism, proteostasis, and mitochondrial impairment, and network-based functions were combined.

Manjunath B. Malshetty, Sandeep Mallya, Sudharshan Prabhu · 0 citations

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