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Author

Manu Mangal

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2 papers indexed here

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Review Sep 2026

Developmental block in ruminant embryos: Mechanisms, molecular insights and potential interventions.

Developmental block remains one of the major hurdles that makes it hard to develop embryos in vitro more efficiently. In ruminants, it is predominantly observed during the 8-16 cell stage, coinciding with the maternal-to-zygotic transition (MZT) and embryonic genome activation (EGA). In addition, reducing maternal tran...

S. Bhatia, Manu Mangal, Priya Dahiya et al. · 0 citations
#gene editing Open access Sep 2026

Optimized cuvette-based electroporation of buffalo and caprine zygotes supports the delivery of up to 21 kilobase plasmids

The advent of precise genome editing technologies has revolutionized the capacity to manipulate animal genotypes and phenotypes, offering a targeted complement to conventional selective breeding approaches. Efficient delivery of exogenous DNA into livestock embryos remains a major technical bottleneck, particularly...

Priya Dahiya, Manu Mangal, S. Bhatia et al. · 0 citations

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