Production and Storage of High-Capacity Adenoviral Vectors for the Delivery of Advanced CRISPR Systems.
Genome editing based on engineered CRISPR systems is advancing rapidly, with the field increasingly moving toward approaches that avoid the induction of mutagenic double-stranded DNA breaks (e.g., RNA-programmable base editing, prime editing, and donor DNA transposition). These nuclease-free strategies often rely on la...
Xiao-Lin Wang, Jin Liu, J. Janssen et al.
· Methods in molecular biology · 0 citations