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María E. Francia

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Open access Jul 2026

Toxoplasma gondii Fatty Acid Elongases are Important for Virulence and Persistence

It is shown that disruption of FAE remodels the parasite lipidome, impairs fitness under fatty acid-limiting conditions, and reduces virulence and chronic persistence in mice, identifying FAE as a key metabolic pathway underpinning adaptation and persistence during chronic infection.

Daniel Walsh, Leandro Tana-Hernandez, Yoshiki Yamaryo-Botté et al. · 0 citations

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