Marjie P. Schmitt

Circadian Biology: Timing Matters in Physiology and Pathophysiology Type 1 diabetes differentially disrupts right and left ventricular daily rhythms

Evidence is provided that the healthy right ventricle (RV), like the left ventricle (LV), possesses an intrinsic circadian clock with robust 24-h rhythmicity, and that diabetes differentially disrupts circadian regulation of the RV and LV, with selective vulnerability of the clock-controlled output genes despite preser...