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Author

Marta Marques Gontijo de Aguiar

2 papers indexed here

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Aug 2026

Pre-clinical evaluation of (2E,5E)-2,5-bis(isoquinolin-5-ylmethylene)-cyclopentanone as a promising leishmanicidal agent.

Investigation of the safety and therapeutic potential of (2E,5E)-2,5-bis(isoquinolin-5-ylmethylene)cyclopentanone (ICP) against Leishmania infantum indicates that it represents an interesting chemical scaffold for further optimization and investigation toward the development of new treatments for leishmaniasis.

Isabela Cristina Soares Martins, T. T. Santos, C. Queiroz-Junior et al. · 0 citations
Jul 2026

A Phytotherapeutic Candidate for Neuropathic Pain: Helicteres ovata (Lam.) Extract Shows Antinociceptive Effects and Favorable Acute Toxicity Profile.

Helicteres ovata extract exhibits significant antiallodynic effect in chemotherapy-induced neuropathic pain, mediated by inflammatory and neuromodulatory pathways and holds promise as a phytotherapeutic candidate for neuropathic pain management.

R. C. de Matos, A. F. A. Bitencourt, Pedro Augusto Lemos Santana et al. · 0 citations

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